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                                    PROteolysisTArgeting嵌合體(PROTACs)分子是非常有前景的新藥開發模式。

                                    PROTAC可以通過誘導目標蛋白的降解來調節蛋白水平,在新作用機制干預方面,比如核酸療法,修飾的多肽,重組蛋白和單克隆抗體等提供助力。

                                     

                                    產品線圖片來源:DOI:10.1021/acs.jcim.8b00872

                                     
                                    產品編號 結構式 項目名稱規格 分子式 加入購物車
                                    A889152 5-氨基-2-(2,6-二氧代哌啶-3-基)異二氫吲哚-1,3-二酮, 95%
                                    5-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione, 95%
                                    C13H11N3O4
                                    B889153 5-溴-2-(2,6-二氧哌啶-3-基)異吲哚啉-1,3-二酮, 95%
                                    5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione, 95%
                                    C13H9BrN2O4
                                    B902516 3-(7-溴-1-氧亞基-2,3-二氫-1H-異吲哚-2-基)哌啶-2,6-二酮, 99%
                                    3-(7-bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione, 99%
                                    C13H11BrN2O3
                                    B902517 3-(4-溴-1-氧代異吲哚啉-2-基)哌啶-2,6-二酮, 98%
                                    3-(4-bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione, 98%
                                    C13H11BrN2O3
                                    D889143 2-(2,6-二氧代哌啶-3-基)-5-硝基異吲哚-1,3-二酮, 95%
                                    2-(2,6-dioxopiperidin-3-yl)-5-nitroisoindoline-1,3-dione, 95%
                                    C13H9N3O6
                                    D889144 2-(2,6-二氧代-哌啶-3-基)-4-氟基-異吲哚-1,3-二酮, 95%
                                    2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione, 95%
                                    C13H9FN2O4
                                    D889155 2-(2,6-二氧代 - 哌啶-3-基)-4-羥基 - 異吲哚-1,3-二酮, 95%
                                    2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione, 95%
                                    C13H10N2O5
                                    H902827 3-(4-羥基-1-氧代-1,3-二氫異吲哚-2-基)哌啶-2,6-二酮, 98%
                                    3-(4-hydroxy-1-oxo-1,3-dihydroisoindol-2-yl)piperidine-2,6-dione, 98%
                                    C13H12N2O4
                                    M889138 4-(2-羥乙基)苯甲酸甲酯, 98%
                                    methyl 4-(2-hydroxyethyl)benzoate, 98%
                                    C10H12O3
                                    M902583 4-(4-疊氮基丁基)苯甲酸甲酯, 99%
                                    methyl 4-(4-azidobutyl)benzoate, 99%
                                    C12H15N3O2
                                    N889139 5-氯-N-(2-(2,6-二氧代哌啶-3-基)-1,3-二氧異吲哚-4-基)戊酰胺, 95%
                                    5-chloro-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)pentanamide, 95%
                                    C18H18ClN3O5
                                    N889154 2-氯-N-(2-(2,6-二氧代哌啶-3-基)-1,3-二氧異吲哚-4-基-乙酰胺, 95%
                                    2-chloro-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)acetamide, 95%
                                    C15H12ClN3O5
                                    N889156 4-氯-N-(2-(2,6-二氧雜哌啶-3-基)-1,3-二氧異吲哚-4-基)丁酰胺, 95%
                                    4-chloro-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)butanamide, 95%
                                    C17H16ClN3O5
                                    N889157 4-氯-N-(2-(2,6-二氧代哌啶-3-基)-1,3-二氧異吲哚-5-基)丁酰胺, 90%
                                    4-chloro-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)butanamide, 90%
                                    C17H16ClN3O5
                                    N903476 3-氯-N-(2-(2,6-二氧代哌啶-3-基)-1,3-二氧異吲哚-4-基)丙酰胺, 90%
                                    3-chloro-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)propanamide, 90%
                                    C16H14ClN3O5
                                    T889137 2-(2-(芐氧基)乙氧基)乙酸叔丁酯, 90%
                                    tert-butyl 2-(2-(benzyloxy)ethoxy)acetate, 90%
                                    C15H22O4
                                    T902580 3-(4-((叔丁基二甲基甲硅烷基)氧基)-1-氧代異吲哚-2-基)哌啶-2,6-二酮, 98%
                                    3-(4-((tert-butyldimethylsilyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione, 98%
                                    C19H26N2O4Si
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